Search on: MAP KINASES, EXTRACELLULAR SIGNAL-REGULATED 
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Descriptor English:   Extracellular Signal-Regulated MAP Kinases 
Descriptor Spanish:   Quinasas MAP Reguladas por Seņal Extracelular 
Descriptor Portuguese:   MAP Quinases Reguladas por Sinal Extracelular 
Synonyms English:   ERK MAP Kinases
Extracellular Signal-Regulated Kinases
MAP Kinases, Extracellular Signal-Regulated  
Tree Number:   D08.811.913.696.620.682.700.567.249
D12.644.360.450.169
D12.776.476.450.169
Definition English:   A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS. 
Indexing Annotation English:   note specifics
History Note English:   2005; for EXTRACELLULAR SIGNAL-REGULATED KINASES use MITOGEN-ACTIVATED PROTEIN KINASES 1994-2004 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38727 
Unique Identifier:   D048049 

Occurrence in VHL:
 

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